Question

In de novo phospholipid biosynthesis, the activated intermediate is CDP-diacylglycerol generated from the reaction of phosphatidate...

In de novo phospholipid biosynthesis, the activated intermediate is CDP-diacylglycerol generated from the reaction of phosphatidate with CTP to yield the CDP-diacylglycerol and pyrophosphate. Based on the chemistry of this reaction, what would you expect to be the source of the two phosphates in the CDP-diacylglycerol?

a. It would be expected that both phosphates would be derived from CTP.

b. It would be expected that both phosphates would be derived from the phosphatidate.

c. One phosphate would be derived from phosphatidate and one from CTP.

Homework Answers

Answer #1

In all of these biosynthesis, and activated intermediate (UDP-glucose, CDP-diacylglycerol, or CDP-alcohol) is formed from a phosphorylated substrate (glucose-1-phosphate, phosphatidate, or phosphoryalcohol) and a nucleoside triphosphate (UTP or CTP).
The activated intermediate then reacts with a hydroxyl group )the terminus of glycogen, the side chain of serine, or a diacylglycerol).

So the Correct answer is C..i.e. One phosphate would be derived from phosphatidate and one from CTP.

Know the answer?
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Not the answer you're looking for?
Ask your own homework help question
Similar Questions
1 In the absence of oxygen, cells consume glucose at a high, steady rate. When oxygen...
1 In the absence of oxygen, cells consume glucose at a high, steady rate. When oxygen is added, glucose consumption drops precipitously and is then maintained at the lower rate. Why is glucose consumed at a high rate in the absence of oxygen and at a low rate in its presence? 2 In the following diagram showing the distribution of thermal energy in a population of substrate molecules, the energy thresholds indicated by numbers represent ... Energy per molecule Number...
READ THE CASE STUDY AND ANSWER THE FOLLOWING QUESTIONS 2nd CASE: An Unexplained Death A 65-year-old...
READ THE CASE STUDY AND ANSWER THE FOLLOWING QUESTIONS 2nd CASE: An Unexplained Death A 65-year-old man of Scandinavian descent was rushed to the Emergency Room of your local hospital after a family member discovered him unconscious in his home. The woman who dialed “911” told the dispatcher that the man, her brother, was the local librarian of the past 10 years and had no spouse or children. She reported that they had spoken the day before, and he had...
I have provided the information for the lab below. I want to see the chemical reactions...
I have provided the information for the lab below. I want to see the chemical reactions that take place during each step of the experiment. So in the procedures when a chemical was added i would like to see what the products and byproducts that were formed. I also want to see one over all reaction for this experiment to just get an overview of what exactly is happening during the experiment. Thank you:) Part B: Synthesis of [Co(NH3)5Cl]Cl2 Objective:...
Please summarize the below article in approximately 100 words: Monumental function in British Neolithic burial practices...
Please summarize the below article in approximately 100 words: Monumental function in British Neolithic burial practices Ian Kinnes The high-risk rate of survival for the non-megalithic series of Neolithic funerary monuments, recently re-emphasized by Piggott (1973: 34), introduces a further variable into the deductive study of burial practices. In Britain and Europe the overall distribution of monumental forms present both lacunae and a marked preponderance of cairns over earthen mounds which are in ill accord with the known or predicted...
Discuss ethical issues that can be identified in this case and the mode of managing ethics...
Discuss ethical issues that can be identified in this case and the mode of managing ethics Enron finds itself in this case. How would you describe the ethical culture and levels of trust at Enron? Provide reasons for your assessment. THE FALL OF ENRON: A STAKEHOLDER FAILURE Once upon a time, there was a gleaming headquarters office tower in Houston, with a giant tilted "£"' in front, slowly revolving in the Texas sun. The Enron Corporation, which once ranked among...
What role could the governance of ethics have played if it had been in existence in...
What role could the governance of ethics have played if it had been in existence in the organization? Assess the leadership of Enron from an ethical perspective. THE FALL OF ENRON: A STAKEHOLDER FAILURE Once upon a time, there was a gleaming headquarters office tower in Houston, with a giant tilted "£"' in front, slowly revolving in the Texas sun. The Enron Corporation, which once ranked among the top Fortune 500 companies, collapsed in 2001 under a mountain of debt...