In the Friedel-Crafts alkylation experiment,
A) What is the purpose of acetic acid?
b)concentrated sulfuric acid
c)why is the reaction performed at low temperatures?
d) suggest two compounds that might be substituted for the t-butyl alcohol in this experiment.
a) Acetic acid act as a solvent for dissolving the compounds.
b) In this alkylation reaction, electrophile that attack benzene is a carbocation which is generated by treating a tertiary alcohol ((CH3)3C-OH) with a strong acid H2SO4 as the dehydrating agent. Advantage of generating the electrophile by this method is that the tertiary cation is a stable and does not rearrange.
c) Reaction is highly exothermic, and should be performed at low temperatures..
d) 1,4-dimethoxybenzene, phenol
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