Which of the following changes would alter the functional characteristics of α keratin? Explain why.
A) Increasing the number of residues per turn to 4.1 while maintaining the same amino acid sequence.
B) Substitution of a hydrophilic amino acid for a hydrophobic amino acid at position ‘a’ and ‘d’ of the 7-residue pseudo-repeat.
C) Decreasing the number of cysteine amino acids within each protofilament.
D) Changing the environment surrounding the protein to one that is more reductive
The correct answers are Option A,B,C and D
A) If we increase the number of residues, then the functional characteristics of alpha-keratin will change because number of residues will affect the functionality of keratin
B) addition of hydrophobic groups will modify the functional character in keratin
C) Decreasing the cystiene will modify the functional character in keratin
D) Changing the enviroment will ask the functional groups to reduce which will lead the functional groups toe change, hence it will affect the functional character
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