Question

A poison is defined as a substance with an LD₅₀ < 50 g/kg
true or false?

Answer 1

LD stands for "Lethal Dose". LD50 is the amount of a material, given all at once, which causes the death of 50% (one half) of a group of test animals. The LD50 is one way to measure the short-term poisoning potential (acute toxicity) of a material.

Toxicologists can use many kinds of animals but most often testing is done with rats and mice. It is usually expressed as the amount of chemical administered (e.g., milligrams) per 100 grams (for smaller animals) or per kilogram (for bigger test subjects) of the body weight of the test animal.

It is a false statement as LD of water 90g/kg for (rat,oral intake),there is no threshold limit for lethal dose and it may vary depending upon nature of toxicant