Question

In a patch clamp experiment, describe the current that flows through a voltage-gated Na+ channel when...

In a patch clamp experiment, describe the current that flows through a voltage-gated Na+ channel when the membrane potential is depolarized.

a. inward capacitive current

b. prolonged inward current

c. transient inward current

d. delayed outward current

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Answer #1

Question: In a patch clamp experiment, describe the current that flows through a voltage-gated Na+ channel when the membrane potential is depolarized.

Answer: c. transient inward current

In response to depolarization, a voltage-gated Na+ channel activates rapidly whcih results in a transient inward current followed by a more slow developing outward current, delayed outward current. Depolarization causes Na+ conductance to decreases overtime to inactivate. The outward current flows through the K+ channels, K+ current activates more slowly than Na+ current and do not inativates.

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