Question

In a patch clamp experiment, describe the current that flows through a voltage-gated Na+ channel when...

In a patch clamp experiment, describe the current that flows through a voltage-gated Na+ channel when the membrane potential is depolarized.

a. inward capacitive current

b. prolonged inward current

c. transient inward current

d. delayed outward current

Science   Biology   
0 0
Add a commentTranscribed image text
Next >

Homework Answers

Answer #1

Question: In a patch clamp experiment, describe the current that flows through a voltage-gated Na+ channel when the membrane potential is depolarized.

Answer: c. transient inward current

In response to depolarization, a voltage-gated Na+ channel activates rapidly whcih results in a transient inward current followed by a more slow developing outward current, delayed outward current. Depolarization causes Na+ conductance to decreases overtime to inactivate. The outward current flows through the K+ channels, K+ current activates more slowly than Na+ current and do not inativates.

0 0
Know the answer?
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Log In

Sign Up

Not the answer you're looking for?
Ask your own homework help question
Similar Questions
You are in the midst of a patch clamp experiment with a single voltage-activated Na channel....
You are in the midst of a patch clamp experiment with a single voltage-activated Na channel. In response to a depolarizing voltage step, the channel current :1) turns on at the onset of depolarization; 2) remains on for a brief period; and 3) turns off (inactivate) before the end of the depolarizing stimulus. a) Draw the voltage step and the current trace from this experiment.
1. If you used the voltage clamp to determine the peak Na current at a membrane...
1. If you used the voltage clamp to determine the peak Na current at a membrane potential of -10 mV, how would you then calculate the peak Na conductance? 2. The K+ current increases as the membrane potential is clamped at increasingly positive potentials? One reason for this is that increasing activation of voltage-dependent K channels results in an increase in gK. What is the other reason?
1) In a neuron, a depolarizing graded potential can directly cause: a. opening of voltage-gated Na+...
1) In a neuron, a depolarizing graded potential can directly cause: a. opening of voltage-gated Na+ channels b. inactivation of voltage-gated Na+ channels c. opening of ligand-gated cation channels d. both a) and b) are correct, and c) is incorrect e. a), b) and c) are all correct 2) Which of the following type(s) of ion channels is/are localized in the synaptic bouton and is/are required for chemical synaptic transmission? a. Voltage-gated Na+ channel b. Ligand-gated ACh Receptor c. Voltage-gated...
Question 4 (3 pts) You are patch-clamping a cell. While holding the neuron at different membrane...
Question 4 (3 pts) You are patch-clamping a cell. While holding the neuron at different membrane potentials, you observed the current recordings below. (1 pt) How many channels does your patch likely contain? (2 pt) Given the recordings above, what is the reversal potential for the channel? Explain your reasoning in 1 sentence. b.(2 pt) Is there any net flow of ions at the resting potential in part ‘b’ above? Why or why not? c.(2 pt) You discover that there...
1. At resting membrane potential in a neuron, which is true of the forces responsible for...
1. At resting membrane potential in a neuron, which is true of the forces responsible for the movement of potassium (directed into or out of the cell)? Select one: a. The chemical gradient is outward while the electrical gradient is inward b. Chemical gradient is inward while the electrical gradient is outward c. Chemical and electrical gradients are directed outward d. Chemical and electrical gradients are directed inward 2. Multiple sclerosis is a devastating disease because it... Select one: a....
Inward synaptic current is effectively blocked through NMDA receptors unless the postsynaptic cell is depolarized in...
Inward synaptic current is effectively blocked through NMDA receptors unless the postsynaptic cell is depolarized in order to: A. generate nitric oxide B. activate adenylate cyclase C. release serotonin D. expel blocking magnesium ions (Mg++) from the pore of the channel E. close the AMPA receptors in a voltage-dependent manner Drugs like Prozac, a widely prescribed SSRI class of drug for depression, work by: A. blocking serotonin receptors B. up-regulating serotonin receptor expression C. blocking the re-uptake of serotonin D....
8. Consider a neuron whose resting potential is -60 mV, and the EK = -100 mV...
8. Consider a neuron whose resting potential is -60 mV, and the EK = -100 mV and the ENa = +40 mV. (a) What is the driving force for Na+, and what is the driving force for K+ at the resting potential? Just give a number, don’t describe what a driving force is in words. (b) What is the relative resistance of the cell membrane for sodium and potassium (i.e. how many times greater or less than the RK must...
8. Consider a neuron whose resting potential is -60 mV, and the EK = -100 mV...
8. Consider a neuron whose resting potential is -60 mV, and the EK = -100 mV and the ENa = +40 mV. a) What is the driving force for Na+, and what is the driving force for K+ at the resting potential? Just give a number, don’t describe what a driving force is in words. b) What is the relative resistance of the cell membrane for sodium and potassium (i.e. how many times greater or less than the RK must...
A) When an alternating voltage of 200 V is applied across a device X, a current...
A) When an alternating voltage of 200 V is applied across a device X, a current of 0.4A flows through the circuit and is in phase with the applied voltage. When the same voltage is applied across another device Y, the same current again flows through the circuit, but it lags behind the applied voltage by π/2radians. Name the devices X and Y. Justify your answer.                                                                   b) A coil of inductance 0.50H and resistance 100 Ω is...
Please No Explanation just ANSWER A,b,c,etc! QUESTION 24 Fifty neurons release excitatory neurotransmitters onto the dendrites...
Please No Explanation just ANSWER A,b,c,etc! QUESTION 24 Fifty neurons release excitatory neurotransmitters onto the dendrites and body of neuron “A.” Neuron A reaches threshold and fires an action potential. This is an example of saltatory summation. continuous summation. spatial summation. temporal summation. Which of the following terms does not belong with the others? sodium IPSP excitatory depolarize 2 points    QUESTION 27 Which one of the following terms does not belong with the others? graded potential depolarizing phase action...
ADVERTISEMENT
Need Online Homework Help?

Get Answers For Free
Most questions answered within 1 hours.

Ask a Question
ADVERTISEMENT