Human immune system has many stimulatory signals which helps recognising foreign bodies, micro flora helps developing immune response which in turn along with epithelial barrier forms defence mechanism against foreign bodies. Host resident bacteria is essential for developing immune response by generating balanced relationships between immune system and micro flora. Host controls the micro flora formation as it is determined by host system since it forms by the composition of diet supplements. Several immune deficiencies that alter microbial communities as it will predispose to diseases, and this suggests the impact of immune system on microbiota composition.
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