Do we see D-amino acids in proteins? When? How common is this?
Ans:
Yes we can see D-amino acids in protein.
Proteins produce D-amino acids next to enzymatic digestion or acid hydrolysis.
Proteins produce D-amino acids by enzyme posttranslational modifications after translation and translocation to ER i.e. endoplasmic reticulum.
D-amino acids are at times found in those proteins which are not synthesized by ribosomes.
D amino acids are not common in living organisms. They are rare in nature.
They are found as components of certain peptide antibiotics in addition in walls of some microorganisms.
After analysis 187 million amino acids are reported in Swiss-Prot database. Out of that D-amino acids reported were merely 837. This shows uncommon nature of D amino acids.
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