Question

Overabundance of epidermal growth factor receptors is a reason for the emergence of some cancers. Suggest a cancer drug that might limit the incidence of a cancer caused by overabundance of epidermal growth factor receptors. You can briefly describe a drug from your case study, or from the online literature, or better yet, you can just make one up. The key part of this question is: what is the mode of action of the anti-cancer drug you are suggesting? How does it work to block cancer?

Answer 1

The tyrosine kinase inhibitors, along with the monoclonal antibodies intercept the pathways of the growth factors in the cancer cells. Other cancer drugs used for the treatment of cancers induced by the over-abundance of the growth factors include cetuximab, panitummab, and nimotuzumab.

The Nimotuzumab is a humatinized antibody that limits the cancer caused by the growth factors by inhibiting the binding of the epidermal growth factors (EGF) to the mutation bearing clones. This inhibition halts the growth of the cancerous cells.