Question

Why is a rare allele more likely to be lost from a small gene pool than from a large gene pool (even if it occurs at the same frequency in both)?

Answer 1

Answer=Due to Genetic Drift a rare allele more likely to be lost from a small gene pool than from a large gene pool.The phenomena of genetic drift is consider due to sampling error.Error rate is less in large sample size comparison to small sample size.

In a small population,the gene frequency exhibits random/non directional fluctuation generation after generation mainly by chance in respective of selective advantage/disadvantage of the gene.In general which allele of the gene become fixed/lost in the population is a matter of chance.This phenomena is known as Genetic Drift/Random Drift.