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The U.S. Food and Drug Administration recently accepted an “emergency use authorization” of a blood test...

The U.S. Food and Drug Administration recently accepted an “emergency use authorization” of a blood test for antibodies against SARS-CoV-2. Describe the cells and mechanism by which antibodies are generated to a pathogen such as SARS-CoV-2.

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Answer #1

antibodies are produced by B cells. B cells develop from the stem cells in bone marrow.

B cells become activated and produce antibodies by differentiating into plasma cells when they encounter a pathogen such as virus and bacteria.

these antibodies then ciruclate in blood to kill the antigen this provides humoral immunity

SARS covid 19 have spiked proteins on its surface if the antibodies are made against it, they can be highly effective as the spiked proteins are responsible for binding to lung epithelial cells where they cause infection.

since antibodies are produced in large number and are present in the plasma of individual they can be transferred like blood to other patients

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