Question

1. DNA contains the hereditary information for the direction of protein synthesis. Each chromosome contains a large number of _____________, which are parts of the DNA molecule.

2.

Professor X studies transgenic mice. These mice express human APP, which causes them to develop Alzheimer’s-like pathology (including the formation of A? plaques). Since the mice do not normally get AD, these mice are examples of human APP ________________ (knock-out/knock-in) mice.

	a.	Knock in
	b.	Knock out

Answer 1

1. DNA contains the hereditary information for the direction of protein synthesis. Each chromosome contains a large number of genes, which are parts of the DNA molecule.

2.

Professor X studies transgenic mice. These mice express human APP, which causes them to develop Alzheimer’s-like pathology (including the formation of A? plaques). Since the mice do not normally get AD, these mice are examples of human APP ____Knock in__________ (knock-out/knock-in) mice.

They are knock in as they are producing the disease. If the gene is removed then it becomes knock out.