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what do we mean by population structure, in cancer cell neoplasm?

what do we mean by population structure, in cancer cell neoplasm?
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Neoplasm is an abnormal cell growth that shows uncontrolled and rapid cell division and differentiation. Neoplasms can be malignant or benign. Population structure refers to the distinct cellular populations that occurs in a cancer. The cancer cells have a genotypically distinct cell populations that proliferate and grow together to form a cellular mass. The population structure differs with different types of cancer. Neoplasms is the beginning of a cancer growth hence the population is not as massive as it is in case of a matured tumor or malignant cancer. The structure of the cell population is distorted as the cells show abnormal growth.

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