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What is the active site of HIV protease which PDB is 4MC1? And why?

What is the active site of HIV protease which PDB is 4MC1? And why?

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The active site of HIV protease mostly includes six amino acids which are triads AspThrGly that is found in each monomer within the amino acid position 25 to 27. If there is a strong hydrogen bonding forces between the Thr26 and Thr26’ residues, it helps in stabilizing the conformational state of the active sites. The function of the Gly27 and Gly27’ is to help and accommodate and bind a substrate in a position. The position must be as such that the catalytic Asp 25 and Asp 25’ carboxylate groups can be attacked.

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