Question

You have discovered a new protein. As part of your analysis you determine its sequence. Within the sequence you find regional stretches that are rich in aliphatic and non polar aromatic amino acids. What could these regions indicate about the location of this part of the protein within the cell? Why?

Answer 1

Aliphatic and non polar Aromatic Aminoacids examples are glycine,valine,leucine, alanine , Isoleucine,proline, phenylalanine, methionine and tryptophan.

Non polar Aminoacids are either aliphatic or aromatic making them hydrophobic ( water fearing) and they do not reside in a aqueous environment.They get buried interior, under the hydrophobic core of the protein or on surface in contact with lipid portion of the Membrane ( membrane bound proteins)

Their presence indicate interior or center of the protein molecules within the cell.