Question

2. Mitochondrial diseases are often caused by mutation in mitochondrial DNA that makes mitochondria dysfunctional. Knowing the function of mitochondria, how would this affect the functions of the cells? _________________________________________________________________________

Even though mitochondria are found in most body cells (except red blood cells), mitochondrial diseases are considered more severe when defective mitochondria are present in the muscles or the brain. Why? ___________________________________________________

Answer 1

Mitochondria is the power house of the cell. It is responsible for the process of cellular respiration leading to production of ATP. Thus, mitochondrial dysfunction will affect entire process of the cell because ATP is the basic requirements for all cellular processes.

The mitochondrial dysfunction is considered more severe in the muscles and brain because muscle and brain require continue energy. Even in the resting condition muscles and brain require energy.