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wha two main proteins comprise the thick and thin myofilaments.

wha two main proteins comprise the thick and thin myofilaments.
Science   Anatomy-And-Physiology   
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Answer #1
  • The two muscle proteins comprise the thick and thin myofilaments are Tropomyosin and Troponin. (Regulatory proteins)

Tropomyosin

  • Tropomyosin is a rod shaped molecule (MW - 70,000) composed of two strands of polypeptides intertwined in an alpha helical configuration with a length approximately equal to seven actin monomers.
  • It is located in the groove between two chains of actin.
  • The function of tropomyosin is to interfere with the binding of myosin head to actin.

Troponin

  • Troponin is a complex of three proteins :
  1. Troponin T : It bind the troponin complex to tropomyosin.
  2. Troponin I : It inhibits the binding of actin to myosin by blocking the myosin binding site on actin.
  3. Troponi c : It binds to calcium.
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