Question

1) a. Explain the effect of the extracellular calcium concentration on contraction strength?

b. How did the active force at the end of the time in the ‘de-oxygenated’ solution compare with that produced by the muscle strip in the normal oxygen-containing solution? Describe this in a quantitative manner.

c. Explain the effect of the ‘de-oxygenated’ solution on the active tension developed by the muscle. What aspect of the heart’s function does this illustrate?

Answer 1

Answer 1(a) - as the concentration of extracellular calcium decreased its Holdings in the sarcoplasmic reticulum rapidly depleted the concentration of calcium in the sarcoplasmic decrease in does the force of contraction also reduces .

increasing the concentration of calcium ions in the plasma leads to increased excitability and contractibility in heart muscle.

although changing the extracellular calcium concentration has a very less effect on the force of contraction of skeletal muscle, but this is not true for smooth muscle and cardiac muscles on increasing The calcium Ion concentration the force of contraction increase is in both smooth and cardiac muscles.