Question

A 54-year-old woman complains of fatigue, lethargy, and weight gain. Serum Total and free T4 are...

A 54-year-old woman complains of fatigue, lethargy, and weight gain. Serum Total and free T4 are abnormally low. If the TSH showed marked elevation, he has Increased cholesterol level, decreased ACE and ALP, anaemia (macrocytic), this would be consistent with:

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Answer #1

Patient symptoms include :

1. fatigue

2. lethargy

3. weight gain.
Laboratory test results of the patient :

1. low T4 levels

2. elevated TSH

3. Decreases ACE and ALP

4. anemia

The above symptoms and laboratory findings are consistent with hypothyroidism.
Hypothyroidism is an endocrine disorder where the thyroid gland is unsble to produce enough thyroid hormone instead of high levels of thyroid stimulating hormone in the body. It is characterised by high levels of serum TSH and low T4. Hypothyroidism also affects the ALT and ACE. This resulting in low levels of ALT and ACE.
Low levels of thyroid hormones results in reduced metabolic rate which causes weight gain, fatigue and lethargy.
Answer : Hypo

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