Question

Give 3 drug examples that have Category X and explain their mechanism of toxic effect type?

Answer 1

The three drugs of X category are the drugs that are contraindicated in pregnant women

Examples of X category drugs are

1) Thalidomide

2) statins

3) oral contraceptives

1) Thalidomide : It inhibits the process of angiogenesis which kills the cells and not given to pregnant women because it crosses placenta and causes angiogenesis

2) Oral contraceptives : It supress the release of gonadotropins and increase risk of thrombus formation

3) Statins : statins decrease the blood cholesterol levels and it causes side effects like congenital anomalies .so contraindicated in pregnant women