Loop diuretics inhibit the ability of the kidneys to reabsorb sodium in the ascending loop. What impact does these loop diuretics have on urine and plasma volume and osmolarity?
For each of the following values would it increase, decrease or stay the same?
1) Urine volume
2) Urine concentration
3) Plasma volume
4) Plasma concentration
Based on the information from this question, what conditions would you treat with loop diuretics?
Thanks in advance!
Ans:-
1) urine vol --- increases since less water is reabsorbed
2)urine concentration decreaeas since water dilute the urine.
3) plasma vol decrease
4) plasma concentrations :- increases as blood become more concentrated.
Loop diuretics are commonly used in the treatment of heart failure. In this condition, fluid accumulates in your body, due to the heart not pumping blood around the body as well as it normally would
Loop diuretics are also used to treat other conditions which cause fluid to build up in the body, such as certain liver and kidney disorders. They are also sometimes used to treat high blood pressure (hypertension).
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