What is the function of the spike proteins on coronavirus?
A. To look scary AF
B. For protection against the immune system of the host
C. To recognize and bind host cell membrane proteins
D. All of the above are correct
Option C-To recognize and bind host cell membrane proteins
Spike protein in a corona Virus is like a multifunctional molecular machine which helps coronavirus to enter into host cells.Spike proteins have 2 Subunits-S1 & S2
*Through S1 subunit,Virus binds to receptor in host cell surface .
*Through its S2 subunit,it fuses viral membrane & host cell membranes and facilitte the entry of Virus into host cell.
The spike protein can occu in 2 structurally distinct conformations- prefusion and postfusion.
when there is a confirmational change from prefusion to Postfusion,There will be fusion of the 2 membranes that helps entry of virus into the cell
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