Fill-out the following Chart
Drug |
Neruotransmitter System(s) (or effector system) |
Nervous System Effects |
Peripheral Effects |
Abuse Potential |
Medical Use |
Barbiturates |
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Benzodiazepines |
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Cannabis |
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Anabolic steroid |
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NSAIDS |
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LSD |
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Ketamine |
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MDMA |
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Cocaine |
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Ritalin |
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Heroin |
Barbiturates are a class of drugs derived from barbituric acid that act as depressants to the central nervous system. These drugs are used as sedatives or anesthetics and have the potential to become addictive. They're problematic because there is no good treatment to reverse a barbiturate overdose.
Barbiturates have been used for physician-assisted suicide (in states where such procedures are legal
This may occur through binding to the receptor for the neurotransmitter called GABA.
So neurotransmitter that is affected is GABA
It effect as a depressent of nervous system and Brain tissue
Peripheral effects include as a control measures for high BP
Barbiturates, once commonly prescribed for anxiety and sleep disorders, can cause death even in small doses - and their abuse is on the rise as is used for inducing sleep
Barbiturates (mainly phenobarbital) are occasionally used by doctors to treat the following conditions:
seizure disorder (epilepsy)
increased pressure in the skull
severe trauma to the skull
some types of convulsions
Barbiturates can also be used as a form of anesthetic.
Off-label uses include treatment for:
migraines
alcohol and benzodiazepine poisoning and withdrawal
jaundice
trauma
However, they are not a popular drug because of the risk of poor outcomes and adverse effects.
Today, it is rare to use them for sleep disorders.
Phenobarbital is most likely to be used for treating seizures. The World Health Organization (WHO) list it as a first-line treatment for epilepsy for adults and children in the developing world, because of its low cost and proven effectiveness.
Barbiturates are available in pill, liquid, rectal, and injectable forms.
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