Question

An important strategy for safely administering Doxorubicin includes:

a. tracking cumulative doses

b.starting the IV in the anticubital fossa

c. assessing for blood return every 15mins

d. reducing dose for serum creatinine less than 3mg/dl

Answer 1

The correct option for above question is Option - b.

Why not Option - a : because of tracking cumulative doses causes dialated Cardio myopathy ( DCM), hence cumulative doses not preferable.

Why not Option - c: assessing for blood return for every 15 minutes not possible, while choosing veins also important because of capillary back of this medicine causes redness, erythromatous plaque formation appeared. That's why we can choose at cubital fossa hece option - b correct choice.,

Why not- option - D- all cytotoxic prodrugs not necessary for dose adjustment in renal insufficiency.

Doxorubicin indicated for cancer for ex: bladder, breast, and also some other type of cancers.