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Cannabis Use and Risk of Prescription Opioid Use Disorder in the United States Mark Olfson, M.D.,...

Cannabis Use and Risk of Prescription Opioid Use Disorder in the United States Mark Olfson, M.D., M.P.H., Melanie M. Wall, Ph.D., Shang-Min Liu, M.S., Carlos Blanco, M.D., Ph.D. Objective: The authors sought to determine whether cannabis use is associated with a change in the risk of incident nonmedical prescription opioid use and opioid use disorder at 3-year follow-up. Method: The authors used logistic regression models to assess prospective associations between cannabis use at wave 1 (2001–2002) and nonmedical prescription opioid use and prescription opioid use disorder at wave 2 (2004–2005) of the National Epidemiologic Survey on Alcohol and Related Conditions. Corresponding analyses were performed among adults with moderate or more severe pain and with nonmedical opioid use at wave 1. Cannabis and prescription opioid use weremeasured with a structured interview (the Alcohol Use Disorder and Associated Disabilities Interview Schedule–DSM-IV version). Other covariates included age, sex, race/ethnicity, anxiety ormooddisorders, family history of drug, alcohol, and behavioral problems, and, in opioid use disorder analyses, nonmedical opioid use. Results: In logistic regression models, cannabis use at wave 1 was associatedwith increased incident nonmedical prescription opioid use (odds ratio=5.78, 95% CI=4.23–7.90) and opioid use disorder (odds ratio=7.76, 95% CI=4.95–12.16) at wave 2. These associations remained significant after adjustment for background characteristics (nonmedical opioid use: adjusted odds ratio=2.62, 95% CI=1.86–3.69; opioid use disorder: adjusted odds ratio=2.18, 95% CI=1.14–4.14). Among adults with pain at wave 1, cannabis use was also associated with increased incident nonmedical opioid use (adjusted odds ratio=2.99, 95% CI=1.63–5.47) at wave 2; it was also associated with increased incident prescription opioid use disorder, although the association fell short of significance (adjusted odds ratio=2.14, 95% CI=0.95–4.83). Among adults with nonmedical opioid use atwave 1, cannabis use was also associated with an increase in nonmedical opioid use (adjusted odds ratio=3.13, 95% CI=1.19–8.23). Conclusions: Cannabis use appears to increase rather than decrease the risk of developing nonmedical prescription opioid use and opioid use disorder. Am J Psychiatry 2018; 175:47–53; doi: 10.1176/appi.ajp.2017.17040413

Homework Answers

Answer #1

Cannabis is a psychoactive drug .It is also known as marijuana, ganja .It causes central nervous system depression and makes the person feel relaxed , sometimes euphoric.

Cannabis use is increasing day by day as a non medical prescription because of its easy availability and the soothing effects which makes individual addicted to it because for them it is a drug which relieves there tension. To get the drug they are ready to do anything and to pay high prices. This makes the people who sell these drugs unauthorisely more powerful and encourages them to sell it at high prices and makes it available to the individuals who needs it. There must be strict laws against this unauthorised sellers of cannabis and punishment should be given to both the person who sells it and to those who uses it .

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