Question

You are referred a 2 month-ald baby girl whose newborn screening electrophoresis showed an "FS" (fetal arid sickle) patterm. You perform parental studies, the results of which are shown here: Mother: Father: Hb A (%) 91 59 Hb A, (%) 1.5 Hb F (46) 3 \ 1.5 Hb 5 (96) 38 You are confused, so you repeat the electrophoresis on the baby and now firid an "FSA (fetal, sickle and small adult hemiogtabin AJ" pattern. What is the most likeiy diagnosis (genotype) of the baby that explains all the laboratory findings? explain

Answer 1

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