Question

A Heparin bolus has been ordered for an ICU patient suffering from pulmonary embolism. Heparin comes from the pharmacy as 25,000 units in 500 ml of D5W. The protocol calls for a loading dose of 80 units of Heparin per kilogram. The patient weighs 100 kg (220 lbs). How many milliliters will be given?

Mr. K has just finished a course of chemotherapy and has a WBC count of 2,000. The order reads Neupogen 5 mcg/kg subcutaneous injection. Mr. K weighs 158.4 lbs. Neupogen (G-CSF) comes 300mcg/ml. How many ml of Neupogen will be required to give the dose? Round to the nearest tenth of an ml

Drug G comes from the pharmacy as 40mg/5cc. How many milliliters will you give to deliver 12 mg of drug?_____

Answer 1

1.

Heparin comes from the pharmacy as 25,000 units in 500 ml of D5W

loading dose of 80 units of Heparin per kilogram

The patient weighs 100 kg (220 lbs)

How many milliliters will be given?

Dose = 80IU/KG

= 80 × 100 = 8000IU

25000IU = 500ML

8000IU = (500/25000) × 8000

= 160ML

2.

Neupogen 5 mcg/kg subcutaneous injection.

Mr. K weighs 158.4 lbs. = 71.85 kg

Neupogen (G-CSF) comes 300mcg/ml.

How many ml of Neupogen will be required to give the dose

Dose = 5mcg/kgT

Total dose = 5 × 71.85 = 359.25mcg

Neupogen (G-CSF) comes 300mcg/ml.

300mcg = 1ml

359.25 = (1/300) × 359.25 = 1.1975ml ~ 1.2ml

3.

Drug G comes as 40mg/5cc.

How many milliliters will you give to deliver 12 mg of drug

40mg = 5cc/ml

12mg = (5/40) × 12

= 0.125×12 = 1.5ml