Question

How should you approach the case in practice ? in the case of ethical consideration ? please answer as soon as possible

Dr. D, a clinical investigator, is conducting a clinical trial on a recently developed therapy for the treatment of a progressive neurodegenerative disorder. While initial results in a previous study generally appeared promising, the therapy has been associated with fatal bone marrow suppression in approximately 1% of patients. A colleague pediatrician, who has a patient with this neurodegenerative disorder, asks Dr. D if the child can be enrolled in the clinical trial. There are no data in the literature about this therapy having ever been used or tested in children with this condition, and Dr. D wonders whether the child should be included in the trial.

Answer 1

Patient consent is the first and the foremost important thing in any research. The research or the trial can be a very rare one or it can take years to find the result but still if the patient is not willing he should not be taken for the Study. Sometime it can be a totally new therapy, treatment or vaccine as in covid 19,volunteers can participate but no one has the right to force anyone into a study. May be can try to convince them by explaining the benefits that they get, the risk involved and the success of the treatment.