Question

A GC sample of a mixture of two compounds produces a single peak in the chromatograph....

A GC sample of a mixture of two compounds produces a single peak in the chromatograph. Give two factors that you could change in the GC experiment to increase the resolution so that the two compounds are separated.

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Answer #1

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1 A GC sample of a mixture of two compound produces a single peak in the chromatograph. Give two factors that you could change in the GC experiment to increase the resolution so that the two compounds are seperated.

Solution: Factors

-The optimising GC over temperature ramp, using a lower temperature rate before the time the overlapping happens.

-Another factor for this problem is reduction in ramping time.

-Optimize the carrier gas velocity (according to Van d method). Probably it is necessary to change the linear velocity of carrier gas. Try to reduce the velocity.

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