Question

Create a sequence of a 21-amino acid peptide that you think would self-assemble into a coiled-...

Create a sequence of a 21-amino acid peptide that you think would self-assemble into a coiled- coil structure. Design one. Underline the hydrophobic and polar amino acids in the sequence.

Homework Answers

Answer #1

The sequence could be

Alanine-Cysteine-Glutamine-Threonine-Phenylalanine -Tyrosine-Tryptophan-Isoleucine-Glutamine -Serine -Aspargine-histidine-tyrosine-proline-methionine-histidine-tryptophan-glycine-cysteine-Asparagine-glutamine

the squence could be as mentioned above

The hydrophobic amino acids are marked bold and underligned

the other are polar amino acid.

The peptide is formed due to amid linkage between amino acids, they undergo coiling due to hydrogen bonds.

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