Question

Which species of streptomycin was originally used to produce streptomycin? Where was this strain of streptomyces isolated from? Who first identified streptomycin as a potent antibiotic?

Answer 1

Answer

The first aminoglycoside, the antibiotic streptomycin, was discovered in 1943 by American biochemists Selman Waksman, Albert Schatz, and Elizabeth Bugie, who isolated the compound from Streptomyces griseus, a strain of soil bacteria.Streptomycin is an aminoglycoside antibiotic produced by the soil actinomycete Streptomyces griseus. It acts by binding to the 30S ribosomal subunit of susceptible organisms and disrupting the initiation and elongation steps in protein synthesis.