Question

Which of the following best describes the formation of the peptide bond between adjacent amino acids?...

Which of the following best describes the formation of the peptide bond between adjacent amino acids?

a. The carboxy end of the amino acid in the P site makes a nucleophilic attack on the ester linkage between the amino acid in the A site (the end of the polypeptide chain) and its tRNA

b. The amino end of the amino acid in the P site makes a nucleophilic attack on the ester linkage between the amino acid in the A site (the end of the polypeptide chain) and its tRNA

c. The carboxy end of the amino acid in the A site makes a nucleophilic attack on the ester linkage between the amino acid in the P site (the end of the polypeptide chain) and its tRNA

d. The amino end of the amino acid in the A site makes a nucleophilic attack on the ester linkage between the amino acid at the end of the polypeptide chain and the tRNA in the P site.

How does the cell know when to stop adding amino acids to a growing polypeptide chain?

a. The translation machinery reaches the end of the mRNA

b. Proteins called release factors recognize stop codons, aiding in the dissociation of the polypeptide chain from the ribosome

c. tRNA’s recognize stop codons and bind a modified amino acid that cannot form a peptide bond

Homework Answers

Answer #1

Answer.

1). d. The amino end of the amino acid in the A site makes a nucleophilic attack on the ester linkage between the amino acid at the end of the polypeptide chain and the tRNA in the P site.

Explanation.

The α-amino group of aminoacyl-tRNA in the A site attacks the carbonyl carbon of the pept-tRNA in the P site to produce a new, one amino acid longer pept-tRNA in the A site and a deacylated tRNA in the P site.

2).

b. Proteins called release factors recognize stop codons, aiding in the dissociation of the polypeptide chain from the ribosome

Know the answer?
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Not the answer you're looking for?
Ask your own homework help question
Similar Questions
In ribosome, a peptide bond is formed by nucleophilic attack of the main chain ____ group...
In ribosome, a peptide bond is formed by nucleophilic attack of the main chain ____ group of the next amino acid to the main chain ____ group of the previous amino acid in amino acid sequence. Select one: a. carboxyl, amino b. amino, carboxyl c. carboxyl, carboxyl d. amino, amino
Carboxypeptidase, which sequentially removes carboxy-terminal amino acid residues from its peptide substrates, is a single polypeptide...
Carboxypeptidase, which sequentially removes carboxy-terminal amino acid residues from its peptide substrates, is a single polypeptide of 307 amino acids. The two essential catalytic groups in the active site are furnished by Arg145 and Glu270. (a) If the carboxypeptidase chain were a perfect α-helix, how far apart (in Å) would Arg145 and Glu270 be? Hint: See Fig 4-4a. (b) Explain how the two amino acid residues can catalyze a reaction occurring in the space of a few angstroms.
4-3.  To demonstrate an understanding of translation elongation, we’ll start somewhere in the middle of translation of...
4-3.  To demonstrate an understanding of translation elongation, we’ll start somewhere in the middle of translation of a polypeptide.  At this moment, the entire ribosome (the small and large subunits) is bound to the mRNA, and there is a tRNA bound at the P-site.  Attached to the 3’-end of this tRNA is the start of the polypeptide- Amino-Met-Leu-Ser-Ala-Phe-tRNA At this starting point, there is no other tRNA bound to the ribosome, and the next codon is 5’-UGG-3’ When the next tRNA binds to...
Place these steps of translation in the correct order. 1. The ribosome attaches to the 5’...
Place these steps of translation in the correct order. 1. The ribosome attaches to the 5’ cap and moves down the mRNA until it finds an AUG within a special sequence. 2. When hydrogen bonds form between tRNA and mRNA, the amino acid attached to the tRNA is connected to the acid end of the peptide chain by specialty rRNA, which catalyzes the peptide bond formation. 3. When one of these codons, UAA, UAG, UGA, is encountered, no tRNA forms...
The type of bond made between 2 amino acids is hydrogen bond? Select one: a. peptide...
The type of bond made between 2 amino acids is hydrogen bond? Select one: a. peptide bond b. hydrogen bond c. amine bonds d. phosphordiester bond e. diester bond
A codon is a series of three bases in mRNA which is equivalent to the 3...
A codon is a series of three bases in mRNA which is equivalent to the 3 bases in DNA; this triplet code corresponds to one amino acid. Once the mRNA is attached to a ribosome, it can assemble the protein by translating from the “language” of nucleic acids to the “language” of amino acids. What is the processed called? In order to synthesize a protein molecule, amino acids need to be aligned in the proper sequence along the RNA sequence....
24 Essentially all of the peptide bonds have trans-configuration to reduce steric clashes between groups attached...
24 Essentially all of the peptide bonds have trans-configuration to reduce steric clashes between groups attached to alpha – carbons of the neighboring amino-acids. Only one of the listed peptide bonds will have a high steric clash irrespective of whether it obtains cis- or trans- arrangement. The amino acid incorporated in such bond can sometimes “break” a peptide chain due to its unique structure. Select the peptide bond with that amino acid. a. Lys-Ala b. Lys-Ile c. Lys-Asp d. Lys-Pro
1. Which of the following amino acids is properly paired with a property? Question options: a)...
1. Which of the following amino acids is properly paired with a property? Question options: a) glycine: contains a polar R group b) proline: presence in polypeptide may cause abrupt change in direction and/or restricted geometry c) leucine: basic amino acid d) aspartate: generally positively charged at neutral pH e) valine: an amino acid that is ideal for the transfer of protons within the catalytic site of enzymes due to the presence of significant amounts of both the protonated and...
1. Which of the following statements about the process of translation is INCORRECT? a. Translation ends...
1. Which of the following statements about the process of translation is INCORRECT? a. Translation ends when the ribosome encounters a stop codon. b. The polypeptide might be attached to a tRNA found either in the “A” site or in the “P” site of the ribosome. c. Ribosomes and initiation factors begin translation by locating the promoter. d. An “empty” tRNA (attached neither to an amino acid nor to a polypeptide) might be found either in the “E” or in...
When is a hypothesis considered scientific? a. when it is based on something other than observation...
When is a hypothesis considered scientific? a. when it is based on something other than observation b. when it can be tested and is refutable c. when it relies on anecdotal evidence d. when it relies on mystical explanations e. All hypotheses are considered scientific until experiments determine otherwise. 3. Of the following, which is the earliest step in the scientific process? a. generating a hypothesis b. analyzing data c. conducting an experiment d. drawing a conclusion e. developing a...