Question

The researchers also identified a number of chemokines and complement components that were upregulated due to...

The researchers also identified a number of chemokines and complement components that were upregulated due to IFNg treatment. Choose one; identify its function and its anti-viral properties.

http://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1005263

Homework Answers

Answer #1

a number of chemokines (CXCL9, CXCL10, CCL8 and CXCL11) and complement components (C1s and C1r) were also highly upregulated by IFNγ

CXCL9, -10, -11 have proven to be valid biomarkers for the development of heart failure and left ventricular dysfunction, suggesting an underlining pathophysiological relation between levels of these chemokines and the development of adverse cardiac remodeling.[6][7]

This chemokine has also been associated as a biomarker for diagnosing Q fever infections.

It has anti-viral property against Ebola virus(EBOV)

Know the answer?
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Not the answer you're looking for?
Ask your own homework help question
Similar Questions
Q1. We are hosts not only to pathogenic microorganisms, but also to a large number of...
Q1. We are hosts not only to pathogenic microorganisms, but also to a large number of different commensals, for example various gut bacteria. How can the immune system distinguish between commensal and pathogenic microorganisms? Q2. An experiment studied the role of the complement system for clearance of bacteria from the blood of mice. Two types of mice were used in the study: C1q-knockout mice and wild type mice. The mice were infected with either antibody-coated or un-coated bacteria (in a...
(Case evaluation, Questions 26-39)             In a study, the researchers were interested in seeing whether if...
(Case evaluation, Questions 26-39)             In a study, the researchers were interested in seeing whether if Ariana Grande’s music can be sexually stimulating to men. The researchers decided to include male students from Hunter College, age ranging from 18-20, without pre-diagnosed sexual dysfunctions. Out of the possible N=10,538 students who meet the criteria for participation, 200 men were randomly selected by computer to participate. After having the participants sign the informed consent, the researchers randomly assigned these subjects into 4...
Q1.Researchers were interested in determining the relative effectiveness of two different brands of eye drops in...
Q1.Researchers were interested in determining the relative effectiveness of two different brands of eye drops in alleviating the symptoms of 'dry eye syndrome'. Forty subjects, who suffered from 'dry eye syndrome', were randomly assigned to receive either brand A or brand B of the eye-drops - 20 subjects to each brand. The eyedrops were administered to each subject and the time until symptoms returned was recorded for each subject. Based on the information provided, which of the following statement/s is...
Due to the growing global concern about climate change, environmental destruction and the increasing number of...
Due to the growing global concern about climate change, environmental destruction and the increasing number of endangered species, ethical consumerism has become an extremely prominent topic. Bertrand and Regan (2008) describe ethical consumption as consciously identifying the links between a product, its origins and the context in which it has been produced. They define the term as awareness of how a consumer’s lifestyle affects people, communities and the environment, and claim that “[an] ethically-informed consumer realises that when they buy...
Case Study 1 Immunology. Directions (3 page maximum). I have identified the disease this man has...
Case Study 1 Immunology. Directions (3 page maximum). I have identified the disease this man has is AIDS (Acquired immunodeficiency syndrome) now I need to; describe what the outcomes of the disease or immunological problem is in the context of the immune system and where might there be deficiencies or problems with the normal immune system function. Lastly, describe how the immune system would be working in a healthy individual. This could include a brief description of how the specific...
This assignment challenges students to formulate a professional response to in-depth issues contained in a real-life...
This assignment challenges students to formulate a professional response to in-depth issues contained in a real-life Video Business Case. Students will act as an independent professional business consultant reporting to senior managers of the company concerned. Students are expected to provide informed and robust advice to this business client. The video below is provided by Ernst and Young company. It refers to the issues faced by an organisation in the Maritime Safety Industry. Ernst and Young is required to solve...
MATH220 Lab04 Due Date: See ACE Excel File: Lab2204-182.xlsx 1 Question 1: (by hand) A retail...
MATH220 Lab04 Due Date: See ACE Excel File: Lab2204-182.xlsx 1 Question 1: (by hand) A retail establishment accepts either the American Express card or the VISA credit card. A total of 30% of its customers carry an American Express card, 70% carry a VISA card, and 20% carry both. a) Find the probability that a randomly selected customer carries at least one of the two credit cards. i) Draw a Venn diagram and shade the region corresponding to at least...
Section C – Mutation of SARS-CoV-2 Over Time All viruses accumulate mutations over time, and different...
Section C – Mutation of SARS-CoV-2 Over Time All viruses accumulate mutations over time, and different classes of viruses have different mutation rates based on the fidelity with which their genomes are replicated. Viral mutations can affect the accuracy of tests, the efficacy of vac- cines, and virulence (the ability to spread, the seriousness of illness, etc.). In this section you will compare a number of sequenced genomes from clinical samples during the first several months of the COVID-19 outbreak...
we are going to speak about the pros and cons of genetic testing and the protections...
we are going to speak about the pros and cons of genetic testing and the protections in place for those who have genetically caused diseases. Please also consider sharing whether you would be genetically tested for a disease and why or why not. This is real life! the topic is about sickle cell disease Sickle cell disease is present at birth, but most infants don't show any signs until they are more than 4 months old. Symptoms of sickle cell...
Findings  In a cohort of 2215 adults with COVID-19 who were admitted to intensive care units at...
Findings  In a cohort of 2215 adults with COVID-19 who were admitted to intensive care units at 65 sites, 784 (35.4%) died within 28 days, with wide variation among hospitals. Factors associated with death included older age, male sex, morbid obesity, coronary artery disease, cancer, acute organ dysfunction, and admission to a hospital with fewer intensive care unit beds. Meaning  This study identified demographic, clinical, and hospital-level factors associated with death in critically ill patients with COVID-19 that may be used to...
ADVERTISEMENT
Need Online Homework Help?

Get Answers For Free
Most questions answered within 1 hours.

Ask a Question
ADVERTISEMENT