Question

Describe the principal regulatory reaction sites in gluconeogenesis and provide an example of the regulator(s) in...

Describe the principal regulatory reaction sites in gluconeogenesis and provide an example of the regulator(s) in each site.

Homework Answers

Answer #1
  1. Gluconeogenesis is regulated by its key enzymes like pyruvate carboxylase which help in carboxylation of pyruvate to oxaloacetate
  2. Phosphoenolpyruvatekinase also help in dercarboxylation of cystol oxaloacetate.
  3. Fructose 1-6 bisphosphatase help in diphosphorylation of fructose 1 , 6 bisphosphate . Glucose 6 phosphatase help in diphosphorylation of glucose 6 phosphate.
  • So these 4 enzyme regulates gluconeogenesis in these rxns . There are some other factors also who regulates gluconeogenesis like hormones glucagon and epinephrine stimulates gluconeogenesis by inducing the synthesis of the key enzymes and insulin inhibits the gluconeogenesis by repressing their synthesis.
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