Question

Name three axon guidance molecules that are prominent in the extracellular matrix. How do neurons detect and respond to these molecules?

Answer 1

The substrate factors that are known to incite axonal development incorporate macromolecules of the extracellular matrix (ECM, for example, laminin (LN) and fibronectin and membrane-bound cell adhesion molecules (CAMs).

laminin as a key ECM molecule to improve neural generation, extension and separation into neurons from hESCs. The cell laminin cooperations include ?6?1 integrin receptors ensnaring a conceivable part of laminin/?6?1 integrin motioning in coordinated neural separation of hESCs.