Question

93. Choose the false statement:

A. Gluconeogenesis and glycogenolysis both occur during the post-absorptive state and generate products that are consumed almost exclusively by nervous tissues.

B. During the post-absorptive state adipose tissues provide triglycerides to most tissues in the body, especially skeletal muscle, in the form of free fatty acids bound to albumin.

C. With regards to addressing the problem of “bad cholesterol”, HDL plays a necessary role as the lipoprotein particle whose function it is to deliver the cholesterol needed for cell membranes to all cells in the body.

Answer 1

Statement 3 is wrong as HDL particles remove fats and cholesterol from cells, including within artery wall atheroma, and transport it back to the liver for excretion or re-utilization.

LDL cholesterol is often called the “bad” cholesterol

Statement 1 is correct......as in the postabsorptive state, ~50% of endogenous glucose production derives from glycogenolysis and the remainder from gluconeogenesis, with the liver accounting for 80% of total glucose influx

Statement 2 is correct as During fasting, adipose tissue, muscle, liver, and kidneys work in concert to supply, to convert, and to conserve fuels for the body. During the brief postabsorptive period, blood fuel homeostasis is maintained primarily by hepatic glycogenolysis and adipose tissue lipolysis.