Question

Which of the following statements is/ are incorrect?

1. high partial pressure of oxygen encourages oxygen unloading at the tissue site.

2. high partial pressure of carbon dioxide encourages oxygen unloading at the tissue site

3. high temperature increases oxygen unloading at the tissue site

4. high 2,3 BPG increases oxygen unloading at the tissue site

5. high pH encourages oxygen unloading at the tissue site

Is it:

a. 1 and 3

b. 2 and 4

c. 1 and 5

d. 2, 3 and 4

e. 5 only

Answer 1

Option 1 and 5 are incorrect.

explanation- the dissociation of oxygen from the hemoglobin occurs in following conditions-

1. Decreased partial pressure of oxygen cause dissociation . At tissue site, there is low oxygen tension so dissociation occur.

2. Increased partial pressure of carbon dioxide. At tissue level, the carbon dioxide level are high due to metabolism, so oxygen dissociation occurs.

3. Increase in hydrogen ion concentration,that is, reduced pH cause dissociation.

4. Increased body temperature cause dissociation.

5. Excessive of 2,3- DPG also cause dissociation.