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What is the stratum corneum and explain what happens to this layer in case of orthokeratosis.

What is the stratum corneum and explain what happens to this layer in case of orthokeratosis.

Science   Anatomy-And-Physiology   
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The stratum corneum is the outermost layer of the epidermis. It consists of 15-20 layers of flattened cellswith no nuclei or cell organelles. Their cytoplasm consists of filamentous keratin. The function of stratum corneum is to form a protective barrier against infection, dehydration, chemicals and mechanical stress.

Orthokeratosis is hyperkeratosis without parakeratosis. Orthokeratosis involves the normal basket weave appearance of the stratum corneum seen in normal skin. In orthokeratosis, the squamous epithelial cells are anuclear.

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