Question

Any chemical that inhibits the action of Acetylcholinesterase (AChase) at the Neuro-Muscular Junction, would cause spastic paralysis of the muscles.

True

False

Answer 1

ANSWER :

The acethylcholinesterase (AChE) enzyme involve in the breakdown of acetycholine neurotransmitter at the neuromuscular junction of skeletal muscles, and prevent the excessive accumulation at these sites to maintain normal ACh mediate neuro-transmission. If a chemical that inhibits the action of AChE at neuromuscular junctions would prevent the essential breakdown of acetylcholine by AChE, and excessive accumulation of ACh would creates muscarinic and nicotinic toxicity that results in muscle weakness, cramps, increased salivation, and some types of paralysis (spastic) includes uncontrollable movements of limbs.

Hence the corresponding statement is true.