Question

1Explain what happens at the neuromuscular junction when a person is taking selective serotonin reuptake inhibitors...

1Explain what happens at the neuromuscular junction when a person is taking selective serotonin reuptake inhibitors (SSRIs) and why SSRIs help a person feel happier.

2What happens if a person stops taking SSRIs cold turkey instead of gradually weaning off?

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Answer #1

1.

Serotonin is known as the happy chemical, decrease the level of serotonin causes many disorders like depression, anxiety, insomnia, etc.

Selective serotonin reuptake inhibitors (SSRIs) increases the level of serotonin in the brain by inhibiting the reabsorption of serotonin into neurons.

Due to the inhibition of reabsorption the serotonin level increases that make a person feel happier.

2.

If a person stops taking SSRIs suddenly instead of gradually weaning off then it can cause antidepressant discontinuation syndrome or antidepressant withdrawal.

In this case, the brain suddenly can not adopt the changes in neurotransmitter level which may gain causes depressions like symptoms or any other symptoms like dizziness, irritability, insomnia, anxiety, fatigue, etc.

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