Eleven-year-old Harry is complaining of a severe sore throat and gets to stay home from school. His pediatrician prescribes a course of broad-spectrum antibiotics, and Harry feels much better within a few days. However, some two weeks later, Harry has a dull, bilateral pain in his lower back and his urine is a smoky brown color. On the basis of Harry's signs and symptoms, diagnose his condition and indicate the relationship (if any) between his present condition and his earlier sore throat. Explain in detail anatomy of anatomy and which part of kidney could have been affected in Harry’s condition.
ANSWER: The patient is diagnosed to have Post-Streptococcal glomerulonephritis. In this case scenario, the patient is first attacked with Group A streptococci which is elicited as upper respiratory tract infection. After two weeks, it is not the bacteria itself causing glomerulonephritis but the body's immune system. Here the kidney is the worst affected organ, also in which the glomeruli is affected. The glomeruli gets inflamed. As glomeruli are the filtering unit of the kidney, urine filtration is affected and results in reductuon im the volume of urine.
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