Question

Consider the use of the ANA (antinuclear antibody) test in the diagnosis of SLE (systemic lupus erythematosus). In a rheumatology practice, the prevalence of SLE in patients on whom an ANA test was done was 2.88% with a hypothetical population of 100,000 patients.

The sensitivity of the ANA for SLE is 98% and the specificity is 93%. What are the True Positives, True Negatives, PPV, NPV, and percent agreement (unpaired) of the test? (Show all calculations for partial credit)

Answer 1