Question

A clinical trial is run to compare the effect of four weight loss programs. What statistical...

A clinical trial is run to compare the effect of four weight loss programs. What statistical test would be most appropriate to use when comparing the weight loss effect between the four programs?

Homework Answers

Answer #1

I think it can be analyzed by univariate ANOVA. Let the body weight be Xij (i=1,...,nj; j=1,...,8), the weight of the ith subject in the jth group. Use the following model to fit your data:

Xij= a+ bi +eij,

where a - overall mean,

bi- the ith group effect, i=1,2,3,4

eij- random error.

You can estimate the parameters by the least squares method and perform hypothesis testing for H0: b1=b2=...b4=0. The F-test can be useful. However, you need to be careful about the assumptions: all groups are independent, normally distributed, and have equal variances. Independence and equal variance may not be easy to validate.

For ANOVA it is extremely helpful to read Fisher's original work.

http://psychclassics.yorku.ca/Fisher/Methods/

PLEASE PLEASE PLEASE LEAVE A THUMBS UP!

Know the answer?
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Not the answer you're looking for?
Ask your own homework help question
Similar Questions
A study of 10 different weight loss programs involved 500 subjects. Each of the 10 programs...
A study of 10 different weight loss programs involved 500 subjects. Each of the 10 programs had 50 subjects in it. The subjects were followed for 12 months. Weight change for each subject was recorded. The researcher wants to test the claim that all ten programs are equally effective in weight loss. (a) Which statistical approach should be used? (i) confidence interval (ii) t-test (iii) ANOVA (iv) Chi square (b) Explain the rationale for your selection in (a). Specifically, why...
A clinical trial is run to assess the effects of different forms of regular exercise on...
A clinical trial is run to assess the effects of different forms of regular exercise on HDL levels in persons between the ages of 18 and 29. Participants in the study are randomly assigned to one of three exercise groups - Weight training, Aerobic exercise or Stretching/Yoga – and instructed to follow the program for 8 weeks. Their HDL levels are measured after 8 weeks and are summarized below Exercise Group N Mean Weight Training 20 49.7 Aerobic Exercise 20...
A clinical trial is run to assess the effects of different forms of regular exercise on...
A clinical trial is run to assess the effects of different forms of regular exercise on HDL levels in a sample of healthy men between the ages of 18 and 29. Participants in the study were randomly assigned to either one of three exercise groups (Weight training, Aerobic exercise or Yoga) or to a control group in which they were assigned to a regular exercise program. Participants were instructed to follow the program for 8 weeks. Their HDL levels were...
What is the appropriate statistical analysis to use: t-test for two independent samples, t-test for dependent...
What is the appropriate statistical analysis to use: t-test for two independent samples, t-test for dependent samples, ANOVA, or chi-square test of independence? Please identify and explain why it is appropriate. (a) A study was conducted to see whether monetary incentives to use less water during times of drought had an effect on water usage. Sixty single-family homeowners were randomly assigned to one of two groups: 1) monetary incentives and 2) no monetary incentives. At the end of three months,...
A clinical trial is run to assess the effects of different forms of regular exercise on...
A clinical trial is run to assess the effects of different forms of regular exercise on HDL levels in persons between the ages of 18 and 29. Participants in the study are randomly assigned to one of three exercise groups (Weight training, Aerobic exercise or Stretching/Yoga) and instructed to follow the program for 8 weeks. Their HDL levels are measured after 8 weeks and are summarized below. Table: HDL mean and standard deviation results for participants of the clinical trial...
A clinical trial is conducted to compare an experimental medication to placebo to reduce the symptoms...
A clinical trial is conducted to compare an experimental medication to placebo to reduce the symptoms of asthma. Two hundred participants are enrolled in the study and randomized to receive either the experimental medication or placebo. The primary outcome is self-reported reduction of symptoms. Among 100 participants who receive the experimental medication, 38 report a reduction of symptoms as compared to 21 participants of 100 assigned to placebo. When you test if there is a significant difference in the proportions...
A clinical trial is planned to compare an experimental medication designed to lower blood pressure to...
A clinical trial is planned to compare an experimental medication designed to lower blood pressure to a placebo. Before starting the trial, a pilot study is conducted involving seven participants. The objective of the study is to assess how systolic blood pressures change over time if left untreated. Systolic blood pressures are measured at baseline and 4 weeks later. Is there a statistically significant difference in blood pressures over time? Run the test at a 5% level of significance. baseline-120...
) Suppose we wanted to evaluate the effect of a diet program on weight loss (in...
) Suppose we wanted to evaluate the effect of a diet program on weight loss (in pounds) using four participants. If µ = 19 and σ = 13, and M = 9, conduct a one-tailed Z-test. B) What can we conclude about the effect of this treatment and explain the result clearly in the context of the study.
A clinical trial is run to assess the effects of different forms of regular exercise on...
A clinical trial is run to assess the effects of different forms of regular exercise on HDL levels in a sample of healthy men between the ages of 18 and 29. Participants in the study were randomly assigned to either one of three exercise groups (Weight training, Aerobic exercise or Yoga) or to a control group in which they were assigned to a regular exercise program. Participants were instructed to follow the program for 8 weeks. Their HDL levels were...
Researchers conducting a clinical trial randomly assigned 60 patients with painful knee osteoarthritis evenly into one...
Researchers conducting a clinical trial randomly assigned 60 patients with painful knee osteoarthritis evenly into one of three treatment groups: glucosamine, chondroitin, or placebo.After the study period, patients were asked if they experienced substantial improvement in pain and ability to function normally.Thirty-four patients replied that they did have an improvement, including 13 in the glucosamine group, 16 in the chondroitin group, and 5 in the placebo group. What statistical test would be appropriate to determine if the three treatments had...