In randomized, double-blind clinical trials of a new vaccine, children were randomly divided into two groups. Subjects in group 1 received the new vaccine while subjects in group 2 received a control vaccine. After the first dose, 101 of 744 subjects in the experimental group (group 1) experienced vomiting as a side effect. After the first dose, 60 of 635 of the subjects in the control group (group 2) experienced vomiting as a side effect. Construct a 99% confidence interval for the difference between the two population proportions, p 1 minus p 2. Use x 1 equals101, n 1 equals744, x 2 equals60, and n 2 equals635. The 99% confidence interval for p 1 minus p 2 is ( nothing, nothing). (Use ascending order. Round to three decimal places as needed.)
Solution:
Given
n1= 744
n2= 635
P1 = 101/744 = 0.1357
P2 = 60/635 = 0.0944
Level
So, the 99 % confidence interval is
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