Question

The American Disease X Foundation reports that 6% of the population over 50 years of age has Disease X. You inquire as to the source of their information, and they cite disease population screening data in the literature which reports that 6% of that population was positive when screened. Referring to the literature, you discover that the screening test used had sensitivity of 95% and specificity of 98%. What proportion of the population over 50 years of age do you think really has the disease?

Answer #1

The 2x2 table for the diagnostic test is define as,

Present | Absent | Total | |

Positive | a | c | a+c |

Negative | b | d | b+d |

Total | a+b | c+d | a+b+c+d |

Given:

and

The American Disease X Foundation reports that 6% of the population over 50 years of age has Disease X such that

Required:

We need to find proportion of the population over 50 years of age who really has disease (positive predicted value)

Now, solving the three equation, we get,

The American Disease X Foundation reports that 6% of
the population over 50 years of age has Disease X. You inquire as
to the source of their information, and they cite disease
population screening data in the literature which reports that 6%
of that population was positive when screened. Referring to the
literature, you discover that the screening test used had
sensitivity of 95% and specificity of 98%. What proportion of the
population over 50 years of age do you...

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Disease
No Disease
Positive screen
80
100
Negative screen
20
800
1. Calculate the
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The main purpose of screening is to identify symptomatic disease
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True
False
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The detectable pre-clinical phase of a disease starts when the
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True
False
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b.
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29-39
40-50
51-61
62 and over
Midpoint x
23
34
45
56
67
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45%
19%
10%
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Does this data indicate that average daily zinc intake in the
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MATH220 Lab04 Due Date: See ACE Excel File: Lab2204-182.xlsx 1
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1. Country A with a civilian non-institutionalized
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