A doctor wants to estimate the mean HDL cholesterol of all 20- to 29-year-old females. How many subjects are needed to estimate the mean HDL cholesterol within 2 points with 99 % confidence assuming s equals 13.7 based on earlier studies? Suppose the doctor would be content with 90 % confidence. How does the decrease in confidence affect the sample size required?
Answer:
Sample size = ( Z/2 * S / E)2
Where,
Z/2 is critical value at given significance level,
S is standard deviation
E is margin of error.
a)
For 99% confidence level,
Sample size = (2.5758* 13.7 / 2)2
= 311.31
Sample size = 312 (Rounded up to nearest integer)
For 90% confidence level,
Sample size = (1.645* 14.3 / 2)2
= 138.33
Sample size = 139 (Rounded up to nearest integer)
So, Sample size required decreases if we decrease in confidence level.
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