Question

A study was conducted among 2,188 patients who were evaluated at autopsy for the presence of Alzheimer’s Disease (AD) or other forms of dementia (Other) by previously established pathological criteria. Patients were also evaluated clinically for the presence of AD.

	Pathological diagnosis
Clinical diagnosis	AD	Other
AD	1643	190	1833
Other	127	228	355
	1770	418	2188

a) If the clinical diagnosis is considered a screening test for Alzheimer’s Disease and the disease 4 status is given by the pathological diagnosis, what is the sensitivity of this test?

b. (What is the specificity of this test?

c. According to this sample, what is the probability that a person has Alzheimer Disease according to both pathological diagnosis and clinical diagnosis?

Answer 1