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A doctor wants to know if a blood pressure medication is effective. Six subjects have their...

A doctor wants to know if a blood pressure medication is effective. Six subjects have their blood pressures recorded. After twelve weeks on the medication, the same six subjects have their blood pressure recorded again. For this test, only systolic pressure is of concern. Test at the 1% significance level. (Calculate "after" − "before.")

Patient:    A       B        C D         E F

BEFORE: 161    162     165     162     166       171

AFTER:     158    159     166      160     167      170

What is the p-value? (Round your answer to four decimal places.)

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