Use the sample data and confidence level given below to complete parts (a) through (d).
A drug is used to help prevent blood clots in certain patients. In clinical trials, among
4924
patients treated with the drug,
170
developed the adverse reaction of nausea. Construct a
99
%
confidence interval for the proportion of adverse reactions.
a) Find the best point estimate of the population proportion p.
Solution :
Given that,
n = 4924
x = 170
(a)
Point estimate = sample proportion = = x / n = 170/4924=0.035
1 - = 1- 0.035 =0.965
At 99% confidence level the z is ,
= 1 - 99% = 1 - 0.99 = 0.01
/ 2 = 0.01 / 2 = 0.005
Z/2 = Z0.005 = 2.576 ( Using z table )
Margin of error = E = Z/2 * (((( * (1 - )) / n)
= 2.576* (((0.035*0.965) / 4924)
= 0.0067
the 99% confidence interval for the proportion of adverse reactions
- E < p < + E
0.035 - 0.0067 < p < 0.035+0.0067
0.0283< p < 0.0417
(0.0283 , 0.0417)
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