Question

Under Kimura-2 parameter model of nucleotide substitution. Calculate the likelihood of the following data: A G...

Under Kimura-2 parameter model of nucleotide substitution. Calculate the likelihood of the following data:

A G T C C A T G A T

A C G T C G T G C T

for 6 genetic distance value between 0 and 1 and plot the results.

Using this plot estimate the genetic distance.

Math   Statistics-And-Probability   
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Answer #1

Given that;

Solution;

  • kimura two parameter(K2P0 model by considering gaps (insertions and /or directions) ans introduce a new measure for estimatic genetic diffrence between two nucleotide sequences interms of nucleotide changes that have occured during the evolutionary process.
  • Using the nuclear ribosomal DNA internal transcribed spacer 2 regions from the genus physalis,We domestrate that species identification and phylogenetic studies strongly depend on evolutionay models .
  • It is especiallynoteworthy that the use of diffrent models affects the degree of over lap between intraspecific and intraspecific diffrences..
  • the other parametres are needed:
  • Hammkng distance
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