Question

4. In a 1985 study of the effectiveness of streptokinase in the treatment of patients who have been hospitalized after myocardial infarction, 9 of 199 males receiving streptokinase and 13 of 97 males in the control group died within 12 months. In this case, you will be asked to practice using two different types of statistical methods to test the hypothesis.

1) If you are going to use proportional test (under normal theory), what criteria needs to fulfill first and perform the result?

2) Use the normal theory method (proportional test) to test for significant differences in 12-month mortality between the two groups. (Z0.975=1.96)

3) Construct the observed and expected contingency tables for these data.

4) Perform the Chi-square test using the contingency table. (X2 1,0.975=3.84)

5) Compare the results obtained from 1 and 3

6) Calculate the odds ratio (OR) and the confidence interval of OR

Answer 1